Serological response to Chlamydia pneumoniae infection

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Serological response to Chlamydia pneumoniae infection.

The human serological response was analyzed by using sera from patients who were serologically positive but isolation negative for Chlamydia pneumoniae and from patients with proven C. pneumoniae infection based on serology and isolation. To assess whether seroreactivity to C. pneumoniae proteins had potential diagnostic value, the cross-reactivities of these sera to other Chlamydia species and...

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Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma.

There is evidence that infection with Chlamydia pneumoniae is associated with asthma of recent onset and that it can influence the severity of asthma. This has led to the suggestion that macrolide antibiotics may be useful in the treatment of asthma in subjects infected with C. pneumoniae. This study examined the association between immunoglobulin (Ig)G and IgA titres to C. pneumoniae and the s...

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Serological response to Chlamydia pneumoniae in adults with coronary arterial fatty streaks and fibrolipid plaques.

The antigen-specific serological response to Chlamydia pneumoniae was studied in 45 adults with coronary artery atherosclerosis and compared with that in 40 adults with acute respiratory infection. C. pneumoniae antigen and DNA were detected in lesions more frequently in patients with low immunoglobulin G titers against C. pneumoniae than in those with high immunoglobulin G titers. Reactivities...

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CD8+ T Cell Response in Experimental Chlamydia pneumoniae Infection

Chlamydia pneumoniae (C. pneumoniae) is a common human pathogen causing a range of respiratory diseases from pharyngitis to pneumonia. Even though the majority of diseases are mild or even asymptomatic, persistent C. pneumoniae infections have been associated with chronic diseases such as asthma and atherosclerosis which represent significant health problems in many countries. Consequently, the...

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Cell-mediated immune response during primary Chlamydia pneumoniae infection.

The development of Chlamydia pneumoniae-specific cell-mediated immunity was studied during a primary C. pneumoniae infection. The immune response was detected as positive lymphocyte proliferation and secretion of interferon gamma. C. pneumoniae-induced activation of both CD4(+) and CD8(+) T cells was detected in the early phase of infection, but activation of only CD4(+) T cells was detected in...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1990

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.28.6.1261-1264.1990